A new IVF technique that reduces the risk of genetic diseases is safe: Study

Jun 11, 2016 | | Say something

IVF-treatment

An innovative IVF based technique that reduces the risk of weakening genetic disorders is passed from mother to child has been found safe, researchers have reported.

Published in the journal Nature, scientists reported an in-depth analysis of human embryos created using the new technique designed to reduce the risk of mothers passing on mitochondrial disease to their children, which is debilitating and often life-limiting.

Mitochondrial disease is a chronic, genetic disease that occurs when the mitochondria of the cell can not produce enough energy for the cell or organ function, according MitoAction, an organization US working to improve the quality of life of adults and children affected by the disease.

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The new technique, called “early pronuclear transfer ‘is transplanted nuclear DNA of a fertilized egg into a donated egg, containing healthy mitochondria, the day of fertilization.

The results of the study involved more than 500 eggs from 64 female donors indicate that the new procedure does not adversely affect human development and greatly reduce the level of defective mitochondria in the embryo.

the results suggest that the technique will result in normal pregnancies, while also reducing the risk of babies have mitochondrial disease.

“This study using normal human eggs is an important advance in our work towards the prevention of disease transmission mitochondrial DNA, “said co-author professor Doug Turnbull paper, director of the Wellcome Trust Centre for mitochondrial Research in Britain.

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“The key message is that we found evidence of the technique is not safe. The embryos created by this technique have all the characteristics to result in a pregnancy,” Turnbull said. Once approved, the new technique allow couples affected by mitochondrial disease have the option of using or not the pronuclear transfer to try to have healthy children read. a genetic disorder makes these girls children when they become 12

‘have overcome significant technical and biological challenges, we are optimistic that the technique we have developed offer women affected the possibility of reducing the risk of transmission of DNA diseases mitochondrial their children, “said lead author of the study Mary Herbert of Newcastle University, England. Read: 60 genetic problems lead to skin and nervous disorders

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Source: IANS

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This article was originally published on thehealthsite, Read the original article here

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Posted in: Diseases & Conditions, DNA, Embryo, Genetic disorder, IVF treatment

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