four universities have given substantial financial support for research on tau plates – the key proteins that accumulate in the brain that causes disease and frontotemporal dementia Alzheimer (FTD).
Scientists at the University of Aston in Birmingham, the University of Cambridge, University College London and the University of Manchester will use stem cells to create a model of tau.
This will help you gain a better understanding of how the protein so that new drugs can be developed works.
Stem cells can be adapted to create other types of cells, allowing researchers to mimic the action of these cells in their laboratories.
If teams can develop the types of cells that are damaged tau, allowing them to try a variety of compounds aimed at minimizing the impact of the protein.
The first phase of the investigation will last six months and the team has been established to have made the greatest progress will be provided with a three-year funding worth up to £ 1 million.
Dr. Eric Karran, director of research at Alzheimer’s Research UK, which is funding the project, said: “We hope that compounds that target this protein could have potential for the treatment of these diseases, but in order to develop a compound of this type it is essential to have systems robust evidence with which to measure the effects of potential drugs accurately.
“the task of these researchers are taking is not an easy task, but this work could have important implications for developing new treatments badly needed for these diseases. “
the competition is being run by the National Center for replacement, refinement and reduction of animals in research (NC3R).
Dr. Vicky Robinson, executive director of the organization, said studies like this not only have the potential to help patients with dementia, which can also reduce costs and reduce the number of animals needed for testing.
This article was originally published on barchester, Read the original article here
Posted in: Diseases & Conditions