HIV mortality rate was halved in rich countries over the past decade

Jul 18, 2014 | | Say something

HIV mortality rate was halved in rich countries over the past decade ;

HIV
A new study has revealed that the overall mortality rate has halved among people with AIDS living in the richest countries in the world and the care you receive and antiretroviral therapy (ART), compared to a decade ago. The study involved nearly 50, 000 adults with HIV receiving care and antiretroviral therapy (ART) in more than 200 clinics across Europe, USA and Australia found that the overall mortality rates have almost halved since 1999, while deaths from AIDS-related and cardiovascular disease causes have decreased by about 65 percent and deaths related to liver more 50 percent.

Although most deaths from causes decreased during the study period, there was a reduction in mortality rates by non-specific cancers of AIDS remained stable over time ( 1.6 deaths per 1000 in 1999-2000 to 2.1 in 2009-2011). AIDS cancers are not the main cause of non-AIDS deaths in people with HIV, accounting for 23 percent of all deaths. Of the 3909 deaths during the study period, about 29 percent of people died of AIDS-related causes, which remains the most common cause of death. Cancers (15percent, mainly lung cancer) were the most common causes of non-specific AIDS deaths, followed by liver disease (13 percent, mainly due to hepatitis), and cardiovascular disease (11 percent). (Read: 12 diseases that affect people with HIV / AIDS )

Mortality was reduced from about 17.5 deaths per 1000 person-years in 1999-2000 to 9.1 deaths per 1000 years in the period 2009-2011, a drop of about 50 percent. Similar declines were also seen in the AIDS-related deaths (5.9 deaths per 1,000 person-years to 2.0), liver disease (2.7 to 0.9), and cardiovascular disease (1.8 to 0.9). The proportion of all deaths due to AIDS (34 percent to 23 percent) and liver disease (16 percent to 10 percent) declined during the decade, while the proportion of deaths from cardiovascular disease remained constant 10 percent. (Read: New, more aggressive strains of HIV now )

Dr. Colette Smith, University College London in the UK, said that these recent reductions in rates of AIDS-related deaths are linked to continuous improvement in the CD4 count and provide evidence of substantial net benefits of ART. He explained further that despite these positive results, diseases related to AIDS remains the leading cause of death in this population and efforts to ensure good antiretroviral adherence and diagnose more individuals at an earlier stage before the development of severe immunodeficiency are important to ensure continued low mortality rate from AIDS is sustained and potentially further reduced. (Read 😕 11 Things about HIV AIDS did not know )

The study is published in The Lancet .

How is the disease diagnosed?

The only way to diagnose HIV is to take a test that looks for signs of virus in the blood. The presence of virus in the blood is called as HIV positive (HIV +). If there are signs of virus in the blood, the result is considered negative. It is diagnosed on the basis of the positive results of two different HIV tests.

on plasma HIV RNA assay (viral load test) when a recent infection is suspected is recommended. The test detects the virus in the blood within 9 days of infection; before the body develops detectable antibodies to it.

Antibody tests: The antibody tests detect HIV antibodies that the body produces in response to infection. In most people, the antibodies to the virus are not detectable for a period of window 3 to 12 weeks after infection. Therefore, a test for HIV antibodies is not useful during this period. Retesting should be done after three months to confirm test results. Some of the antibody tests are as follows:

  • rapid HIV antibody test , the test most common HIV it is carried by the blood, urine or saliva and can produce results within an hour.
  • enzyme-linked (ELISA) is an antibody test which is usually the first to be used to detect HIV infection. If the result is positive, the test is usually repeated to confirm the diagnosis.
  • Western blot test is one of the oldest confirmatory tests antibodies, but more accurate. It is done to confirm the results of two ELISA tests positive

polymerase chain reaction (PCR test viral load ) test finds either RNA or HIV DNA in white blood cells, even if other tests are negative for the virus. The PCR test is very useful to find a very recent infection, screen blood for HIV before donation and in babies born to mothers infected with the virus.

The p24 protein, HIV antigen that produces an antibody response in the body is overproduced onset of infection. p24 antigen testing detect these proteins in the blood. This test is usually not used for general purposes of diagnosis of HIV.

people living with HIV may not have any symptoms of the disease for eight to ten years or (asymptomatic period) longer. His (T cells) CD4 count should be monitored closely during this time. If you have an account of CD4 below 200 and / or AIDS-related conditions appear, then it is considered to have AIDS . Read more about Living with HIV – diagnosis, treatment and prevention

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with inputs from ANI

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This article was originally published on thehealthsite, Read the original article here

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