The prognosis for a woman experiencing atrial fibrillation may be worse than a male counterpart.
Atrial fibrillation (AF) is associated with an increased risk of Career and death in general, with an estimated 33.5 million people affected worldwide in 2010, and a mortality rate adjusted for age of 1.7 per 100,000 people.
The prevalence is increasing in developed and developing countries.
This could have important implications for estimating the burden of AF, treatment guidance for management and for future research on gender differences.
An international team of researchers set out to estimate the association between AF and cardiovascular disease and death in women and men and to compare gender.
In a meta-analysis of 30 studies published between January 1966 and March 2015, the data of more than 4 million participants were analyzed.
12% increased risk of mortality of women with FA
All studies had a minimum of 50 participants with FA and 50 without, who reported specific associations of each sex between AF and mortality from all causes, cardiovascular mortality, stroke, cardiac events – including cardiac death and myocardial infarction nonfatal – and [19459018insuficiencia] heart .
differences in study design and quality in order to minimize bias taken into account.
AF was associated with a relative risk of 12% higher all-cause mortality in women and a much higher risk of stroke, cardiovascular mortality, cardiac events and heart failure. The reason for gender differences is not known.
With regard to clinical care, the results support the development of a score of specific risk for AF in women and more aggressive treatment of risk factors in women, as recently recommended by the American Heart Association ( AHA).
In relation to public health policy, researchers say estimating global and regional burden of FA should be independent of sex, while “the allocation of public health resources for the prevention and treatment of AF also You should consider the differential effects of FA sex. ”
Finally, they say future research should try to determine the underlying causes of the observed sex differences.
In view of the results, the authors conclude:
“It may be desirable that physicians consider more aggressive treatment of risk factors in women with FA, as they seem to be at higher risk of death proportional and cardiovascular disease.”
Medical News Today previously reported on research showing that there no relationship between coffee consumption and atrial fibrillation .