How you age depends on many factors, and hormonal balance is a key element in which, as he explains nutritionist Patrick Holford.
Hormones, with its power to reverse the effects of aging and increase sexual activity, has always been regarded with a mixture of fascination and alarm. In the first half of the last century, before testosterone or estrogen were synthesized, they had lurid accounts of the wealthy elderly men who have an adventurous form and eye watering anti-aging medicine by grafting testicles crushed chimpanzees and other mammals on their own which, according to them, was very rejuvenating.
Much more concern and confusion now focuses on HRT (hormone replacement therapy), which is composed of synthetic versions of the ‘female’ hormones, estrogen and progesterone. The apparent cure turned out to have a dark side, when he found that HRT to actually increase the risk of heart disease and breast cancer after the big Initiative study of Women’s Health in 2002.1 This has left millions of women in their forties and fifties in a quandary. You are deciding on the benefits of hormone replacement therapy and hope to avoid the side effects? Or do you stay out of it and hope to find something else? official medical advice is to use short term – two years – is not linked with an increased risk. However, many have stopped taking it. Following the 2002 study, the number of prescriptions in the UK and the US It has been halved. In the years since there has also been a significant decrease in the number of breast cancers.2
Natural vs Synthetic hormones
There is no solution used widely in the US, but little known in the UK. This is the same hormones found in therapy normal hormonal replacement, but come in a slightly different form known as “bio-identical”, which means they are exactly the same as his body was doing until he reached andropause menopause or in the case of men. Those used in hormone replacement therapy are not identical, and this is most likely the reason for the problems that have caused; for example, a type of estrogen is still widely used (over 500,000 recipes were issued only in England in 2010) is known as conjugated estrogen and comes from the urine of pregnant mares, which contains types of estrogen normally only They found in horses. The best known brand is Premarin, and this was used in the assay Health Initiative of Women.
Replacement of progesterone used in hormone replacement therapy normally known as progestin (or progestin), and the best known brand is Provera. Also it has a significantly different chemical structure of progesterone. This is related to the very different effects both have: Progesterone is the hormone that is produced in large quantities during pregnancy, it is also a diuretic, and the risk of blood clots is decreased, has antidepressant effects and helps form bones. Progestins can cause miscarriages, fluid retention and blood clots, and is linked to mood swings and can reduce bone density.
hormones decrease with age
The fact is that hormone levels often decrease dramatically make later in life. Testosterone deficiency can result in lack of sexual desire, lack of motivation and depression in both men and women. The lack of estrogen results in vaginal dryness and lack of progesterone, you can do all these hormones, resulting in lack of everything. In addition, progesterone dampens adrenal hormones so a common effect of progesterone deficiency is more anxiety, angry outbursts, insomnia, muscle tension and pain, all of which are often found in menopause.
Progesterone is the “mother” of all hormones, it made from cholesterol. (Beware enthusiasts statins -. Lead cholesterol too low, for example below 3.5 mmol / l could lead to hormone deficiency)
The body always make cortisol – the stress hormone – in preference to anything else, because it has to do with our immediate survival. This reality can not be the case when stressed watch the news, but your body thinks it is. Accordingly, DHEA levels are low. The more stressed you are the higher cortisol and lower DHEA is, until completely burn in which case both low. This in turn means less DHEA to manufacture testosterone. Chronically low levels of DHEA is one of the consistent indicators that are aging faster than their chronological age, so it has become a popular supplement.
DHEA – Do You Need It
DHEA is the most abundant in the body hormone, but production for both men and women peaks at age 20 and it is reduced to half that rate at 40 years, and at the time they are 65 will only be producing 10 to 20 percent of your youth level. It is part of the pathway that produces sex hormones, so it is likely to have an impact there and is also the hormone that balances cortisol, a stress hormone. This means that low levels can reduce the effectiveness of the immune system, which becomes less sensitive when stressed. So there is certainly a logical step for the restoration of case levels. DHEA supplements benefit mice, but there is still no hard evidence that slow aging in humans.
Symptoms of deficiency include:
Unable to cope with stress
Disunity or motivation
Your body naturally produces DHEA 35-60mg one day, which can be measured accurately in both saliva and blood. Practitioners are likely to prescribe between 15 mg and 50 mg. If you are taking DHEA, then you should recheck your level after about 90 days. Sometimes I recommend to people who are burned out only for a month, at a dose of 25 mg.
The other way to increase your level of DHEA is to reduce stress and reduce your cortisol level. Some very simple exercises that can do this have been developed by the HeartMath Institute (see my report on HeartMath They are designed to eliminate loops negative thoughts and promote the sustained positive emotional states. In a study of 45 volunteers, 15 who did the exercises for a month, watching the fall of cortisol by 23 percent, and increased level of DHEA in 100 percent.3 also reported feeling less stressed and more positive. there were no changes in the other.
Many experts believe that the hormone all post-menopausal women should be at physiological levels of progesterone, because none is produced by the ovaries after menopause and your body uses it to make the rest of the hormones it is necessary to protect their bones. stimulation of osteoblasts that build bone, while estrogen dampened by the demolition team of osteoclasts. In fact, it could be that progesterone plays a more important role in bone protection that estrogen role. Women who have periods when no progesterone is produced – known as anovulatory – begin to lose bone mass; 4 however, the results of trials using progesterone to protect bones have been mixed; for example, one found that was four times more effective than hormone replacement therapy of estrogen, without any of the associated risks, in May while two others found no effect, although the symptoms of menopause, such as hot flashes and night sweats, were reduced.6
Could it be poor? These are the symptoms to consider:
anxiety, depression, irritability and mood swings
Loss of bone / increased risk of osteoporosis mass
Increased pain and inflammation
If you have two or more positive responses that could well benefit from seeing an expert. But how can you be sure that you will not be the same risk of cancer than women taking hormone replacement therapy? You can not be absolutely sure, but there is no evidence that the combination of estrogen with progesterone is much safer than the combination of estrogen and progestin. Inevitably, randomized trials have not been done, but not a very interesting natural experiment underway in France, where progestins and progesterone are both widely used, because some women prefer one and some another.
The researchers followed more than 80,000 women to see what happens with each group, and the result was a convincing win for progesterone, which caused no increase in cancer. Those who received the combination of progestin, however, had raised the risk by 69 percent. Taking estrogen alone increased the risk by 29 percent.7
during middle age, the level of the three hormones estrogen a woman begins to decline, because these hormones are no longer required to prepare the lining of the uterus for pregnancy. One effect of this is that the menstrual flow becomes lighter and often irregular, until finally stops completely. Other signs of a decreased level of estrogen include:
Slimmer, skin older with more wrinkles
Increased risk of urinary tract infections
desire loss of bone mass
again, if they look familiar, you might benefit from being unprotected. Even if your estrogen level is low, it still might be suffering from a condition called “estrogen dominance”, whose symptoms include fluid retention, breast tenderness, mood swings, weight gain around the hips and thighs , depression, loss of libido and cravings for sweets. This seems contradictory, but it is because estrogen and progesterone must be kept in balance. So if you are in your forties and anovulatory periods have, you could be in a state of estrogen dominance, although estrogen is low, because their progesterone levels are even lower.
The result may be too many growth signals to cells of the breast and uterus, increasing the risk of cancer. This is why you need a good practitioner. Only the replacement of low estrogen without checking what is happening might not make you feel better and could lead to cancer.
To further complicate things, that not only replace ‘estrogen’. It comes in three varieties – oestrodial, estrone and estriol. And besides, they are present in very different proportions. Estriol is that weaker women, and premenopausal usually have lots of it; which constitutes about 90 percent of the total amount. The next most abundant is estradiol, the most potent, about 7 percent, followed by estrone 3 percent.
practitioners bio-identical tested to find the proportions of estrogen and then prescribe accordingly. “I often find that estrone levels are elevated in postmenopausal women,” says Dr. Gluck ‘while estradiol and estriol are too low. “More than half of patients progesterone are prescribed together with a combination of estradiol and estriol bio-identical.
Hormones affect almost all parts of your system so that, logically, when their levels fall too low can suffer a wide confusion range of symptoms – and most of these can also be caused by something else If you have been suffering from any! following for a while, it pays to have your hormones checked to see if they could be contributing
• anxiety, depression, irritability and mood swings
• Increased pain, swelling and pain joints.
• insomnia, night sweats and weight gain
• Slimmer, skin older with more wrinkles
• Decreased libido and lack of energy and drive
• Confusion and memory problems
depending on your symptoms and test results can be a real benefit in correcting hormones that are deficient in using bio-identical hormones, with the equivalent dose at which your body would normally produce. I recommend that you re-evaluated after three and six months, as some hormonal imbalances so you will not have to keep taking as much corrected. Natural hormones will extend their healthy lifespan? The odds are good, but there is no definitive proof yet.
To learn more read my book The 10 secrets of healthy aging.
J. E. Rossouw, et al, “The risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results of the Health Initiative randomized controlled trial Woman”, Journal of the American Medical Association, 2002; 288 :. 321-33
. Tehillah S., et al, “The rates of atypical ductal hyperplasia decreased with reduced use of postmenopausal hormone treatment results of monitoring breast cancer Consortium ‘, Cancer Epidemiol Biomarkers Prev 2009: 2822-2828; doi: 10.1158 / 1055-9965.EPI-09-0745
R. McCraty, et al, “the impact of a new program of emotional self-control on stress, emotions, heart rate variability, DHEA and cortisol ‘integrative and physiological and behavioral science, 1998; 33 (2) :. 151-70
Before J., et al, “spinal bone loss and ovulatory disorders,” New England Journal of Medicine, 1990 ;. 323 (18) 1221-7
J. Lee, “reversal osteoporosis: the role of progesterone, “International Journal of Clinical Nutrition, 1990; 10: 384-91; see also J. Lee,” osteoporosis with transdermal progesterone investment, “Lancet, 1990; 336 (8726) :. 1327 [
A. Cooper, et al, “systemic absorption of progesterone cream from Progest in postmenopausal women ‘, Lancet, 1998; 351 (9111): 1255-6
A. Fournier, et al, “unequal risk for breast cancer associated with different hormone replacement therapies: results from the E3N cohort study ‘treat breast CancerRes, 2008; 107 (1) :. 103-11
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