Not all low-nicotine cigarettes reduce harm to smokers

Oct 1, 2016 | | Say something

Skip to content reduced nicotine (RNC) of cigarettes may not necessarily reduce harm to smokers, according to a new study by Penn Center for Interdisciplinary Research on nicotine addiction (Cirna). Smokers also tend to ignore precautions contained in the box warning labels, the authors found in a separate study.


 Not All Low Nicotine Cigarettes Reduce Harm To Smokers Not all low-nicotine cigarettes reduce harm to smokers

The study results were recently published in Cancer Epidemiology Biomarkers and Prevention and dependence on drugs and alcohol. RNC cigarettes are a new type of cigarette containing various levels of low nicotine and are constructed differently than light cigarettes.

‘reduced nicotine content (RNC) cigarettes are a new type of cigarette containing various levels of low nicotine and are constructed differently than light cigarettes. It may not necessarily reduce harm to smokers. “

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The first study was a randomized clinical trial showed that cigarette smokers more used daily and had greater exposure to cigarette smoke when administered with levels slightly lower than its own brand nicotine; and they increased their swelling when the very low nicotine level cigarettes, nicotine and smoke exposure are provided decreased overall. In the second study, researchers experimentally altered ads for these same cigarettes RNC and found ways to correct some of the misconceptions are smokers about the risks associated with smoking low-tar cigarettes.

The research, led by Andrew A. Strasser, PhD, associate professor of psychiatry and director of the Laboratory of Penn Biobehavioral smokers in the Perelman School of Medicine at the University of Pennsylvania professor, can inform policy under the Food Administration and Drug Administration (FDA) control Act snuff.

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The trial randomized 158 smokers do not seek treatment who participated in a study of 35 days to examine the behavior of the topography of smoking, or how a person smokes a cigarette (including the number of inhalations and volume of puff pastry, duration and speed ). After an initial period of five days of 80 participants were randomly assigned to an experimental group and were asked to smoke three levels of progressively decreasing cigarettes RNC (for three periods of 10 days), and 78 participants served as a control group he smoked their own brand of cigarettes throughout the study. The researchers assessed the smoking behaviors and took blood samples to test several biomarkers throughout the study.

“Of particular interest is that when cigarettes level of moderate nicotine smoking, participants consumed more cigarettes a day, but swollen each less intensity than when his own name or as compared to the control group smoked. But then the daily consumption of cigarettes decreased swelling and increased intensity for the lowest cigarette nicotine, illustrating the complexity of the assessment of patterns of cigarette “Strasser said. “To further add to the complexities, our measures of smoke exposure significantly decreased for cigarette lower nicotine compared with the control group, but nicotine cigarettes intermediate level increased some exhibits toxic, while decreasing the rest.”

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The second study eye-tracking technology was used to examine how smokers see 202 cigarette advertising in order to better understand how to effectively convey the risk for smokers. Specifically, the study focused on whether anti-advertising and corrective messages – such as adding information in ads that report that lower smoking nicotine does not mean less health risks – could improve understanding of smokers of the risks .

The results of visual monitoring showed that most smokers do not look at the box warning label is located in ads snuff, so the text only warning areas that are currently in many ads an ineffective way to transmit risk. With the inclusion of risk information in the body of the ad, smokers were more likely to look, remember and believe that their risks of using snuff product. The researchers suggest that these results could support the regulation of how products are marketed snuff.

“The Law on Control of Snuff allows the FDA to regulate the marketing of snuff and advertising so that people are not deceived about the damage, and the FDA may also establish rules on the constitutive levels of smoking, including nicotine, if scientific evidence supports that will benefit public health, “Strasser said. “While these studies are scientifically very different, their results can collectively inform policy and future law by regulating the RNC ways can be marketed, as well as the identification of nicotine levels in optimal cigarettes to reduce exposure to They are containing hazardous substances. ”

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Melissa postdocs Lochbuehler Mercincavage and Kirsten were the first authors of these publications, which also included researchers from Penn Wileyto and Paul E. Joseph N. Cappella.

The Center for Interdisciplinary Research on Nicotine Addiction was created in the Department of Psychiatry at the University of Pennsylvania School of Medicine Perelman in 2001. Continuously funded by a P50 Transdisciplinary Use of Snuff Research Center grant from the National Cancer Institute and the National Institute on Drug Abuse, and additional support extramural researchers Cirna conduct interdisciplinary research focused on improving understanding and treatment of nicotine dependence. The major research collaboration of researchers Cirna ranges from “cells” for society, that cross departments and schools of the University of Pennsylvania and extend to institutions across North America.

This work was funded by the University of Pennsylvania Center Snuff Regulatory Science (P50 179 546), a center funded by an initiative of the FDA / NIH grant and the National Cancer Institute (R01-180929 and R01- 120,594).

Source: Newswise

This article was originally published on medindia.net

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