Having a regular schedule means you will live a longer and healthier life.

Jun 16, 2016 | | Say something

Having a regular schedule means you will live a longer and healthier life. ;

Dr. Olisa Mak, ND

For years, my mother worked the night shift at the hospital in Vancouver as a respiratory therapist ER. During the day she was a housewife, taking care of my brothers and I, leads us to school, and our extracurricular activities. Over time, this lifestyle took a toll on his health and became very clear that she had only two choices – he quit his job or understand that his body let him down. Since his retirement, his health has deteriorated and only after 15 years of making healthier, more balanced dietary choices and exercise more, your body has begun to repair itself.

In Canada, approximately 4.1 million of the 14.6 million or 28% of employees do not work a normal day shift. 1 is a well known fact that irregular working hours causes insomnia and fatigue and wear done. . Less well known is that it also increases the risk of obesity, type 2 diabetes and hypertension 2 In recent years, a better understanding of the circadian rhythm has developed – explain how an altered circadian rhythm increases the risk of disease chronic, and how a balanced circadian rhythm is key to maintaining a longer and healthier life.

Novel research confirms a complex system clocks are closely synchronized with variations of light and sleep / power cycles. 2 master body clock, located in the brain, tuned to perceived changes in light and sets the time for the whole body. 2 individual organs such as the heart, thyroid and liver, also have their own clocks. 2 clocks communicate with each other through a system of nerves and hormones, 3 as the endocrine system or digestive system.

As the master clock sets the pace and the other watches follow the activity of every organ and cell is synchronized. Synchronicity ensures that the body’s needs are met at any given time. For example, when the body waiting for a meal, the master clock communicates with organs (especially liver) cells to synthesize and glucose transporters and required to metabolize glucose inrush enzymes. 4 should work synergistically individual watches as the body’s needs change throughout the day. The system also ensures that conflict metabolic processes occurring at different times of day. 5 As the time on clocks change, each organ can be seen as a completely different body. 2

The specific genes involved in the regulation of circadian clocks have now been identified and are being studied in humans and animal models. We are beginning to understand the function of specific genes, how genes interact and how the expression of these genes changes throughout the day. More importantly, the research strives to understand the process of circadian desynchronization and its potential clinical applications, especially increasing number of people who work irregular hours.

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The circadian rhythm and liver

Research shows that the circadian rhythm affects organ function by inducing temporary changes in gene expression. These changes have been most extensively investigated in the liver. Genetic analysis shows that 5 to 20% of changes in liver DNA according to the circadian rhythm throughout the day. 2 All aspects of liver function is regulated by the circadian rhythm of the body from cholesterol metabolism, detoxification, conversion of thyroid hormones, and the synthesis of clotting factors that control bleeding . 4

The liver plays a unique role in how our body responds to our environment. Suboptimal liver processing of potentially toxic chemicals daily hygiene products, pesticides, pollution and the food is often the underlying cause of chronic disease. A better understanding of the circadian regulation of liver detoxification pathways strengthen our defense and resistance against various environmental stresses. When specific circadian rhythm genes are eliminated, the mice show premature aging syndromes and widespread deficits in liver detoxification. 4

Alcohol undoubtedly emphasizes detoxification pathways of the liver and liver desynchronizes clock from the master clock. 2 As the clock liver is disconnected from the system, liver activity and function it is no longer addresses the needs of the body at a certain time. The researchers suggest there may be times during the day when the circadian clock is more vulnerable to the harmful effects of alcohol, times when it is best to avoid alcohol. 2 Unfortunately (or fortunately), that time is still to be determined, but the implications are monumental. Laboratory studies also show that average alcohol changes in bowel clock. 2

All health products (supplements, herbs, drugs) orally is processed by the liver before going to target organs. As liver functions as organ completely different depending on the time of day 2 treatments implemented at different times of day may give better results with fewer side effects. In a study, taking antihypertensive night (compared to the morning) showed a greater reduction in cardiovascular events (CVD) and cardiovascular mortality 5 .

The circadian rhythm and diabetes

The (high or low) extreme levels of glucose levels are medical emergencies that threaten life. Together, the teacher and the liver clock clock modulate basal glucose levels, and regulation of hormones glucagon and insulin. 4 This ensures that glucose levels are kept within safe physiological range, regardless of fluctuations in sleep / wake cycles and feeding. This has huge implications for the treatment of type II diabetes. Diet, poor lifestyle choices and irregular work schedules are all risk factors for developing type II diabetes. 2 Understanding the degree of effect of circadian dysregulation has on insulin and glucose levels are also shown the extent that lifestyle choices contribute to the disease process. This would allow naturopathic physicians to better predict the magnitude of benefit from dietary recommendations and lifestyle that are cornerstones of type II diabetes treatment.

The circadian rhythm and diet

A meal rich in a particular type of nutrients, fats, proteins or carbohydrates, has different effects on the body when consumed at different times of the day . People who regularly eat high fat meals at the end of the day are more likely to increase the synthesis of fat, have high cholesterol and fat), and cardiac dysfunction. 2 In another study, rodents were forced to eat during times when they should have been sleeping and gene expression in all organs clocks shifted by 12 hours. 2 These same mice also showed significant weight gain.2 we could finally have the answer to why midnight or mid-morning snack might not be the best idea.

What does this mean for future medicine and health

furthering our understanding of the waves of the circadian system in almost all areas of health. an idea and hope the conditions in which the circadian dysfunction is common that do not yet have a cure, such as schizophrenia 6 , Alzheimer’s disease, Parkinson’s and Huntington disease occurs. 7 which means the implementation of preventive strategies above conditions in which the circadian dysfunction is a risk factor. 4 is that it provides the most accurate and reliable prognostic factors.

Heart attack of a certain nature (STEMI) are more likely to occur in the morning 5 Accordingly, symptom onset time could be a factor of better prognosis than the prognosis factor current used -. Duration of restricted blood. flow 5 This brings us to the question of whether current rules and procedures are up research is showing. more research is needed.

novel treatment targets that recognize the natural circadian body-induced fluctuations could mean better results. Research suggests that normalization of blood sugar levels before and after breakfast should be the primary goal of treatment for diabetes. 5 levels of blood glucose in diabetes not remain constant during the night while diabetic patients have a high level of glucose in the morning before breakfast. 5 statement of the adrenal gland of the stress hormone, cortisol, also follows a circadian rhythm. 5 In healthy individuals, cortisol levels peak before waking and decrease during sleep. 5 replacement therapy for conventional glucocorticoid adrenal insufficiency often leads to bad results, because not imitate this natural pattern of 24 hours. 5


Like a film director, the circadian rhythm directs everything that happens behind the scenes, the function of all organs and cells coordination. Circadian improve health undoubtedly it promotes the health of the whole body.

Our most current understanding of our circadian clocks highlights the risks of working long hours, night shifts or even motherhood. All of which are associated with an increased risk of dyslipidemia, obesity, Type 2 diabetes and hypertension. 2 The key to living a longer and healthier life is to have a regular schedule and for those who are unable to do so, understanding the effects of a disrupted circadian rhythm and mitigate these effects. Addressing the Circadian deregulation will not only improve your overall health, but also slow aging and reduce your risk of developing several chronic diseases.

Maintaining a healthy and balanced circadian system can be done by having a regular sleep, eat and schedule of activities. A regular schedule allows the body to anticipate and prepare for varying environmental demands or stress 2 , for example, by the production of digestive more in the preparation of a food enzyme, so that absorption can continue . Experience a longer and healthier life with a digestive sharper and faster mind, higher energy levels and better heart, and reproductive health.

3O1C9913 no necklace Olisa Dr. Mak is a licensed ND with a family physician general in downtown Vancouver. She has a special interest in bringing awareness of the mind-body connection using homeopathy, botanicals and life style advice.
She is driven to educate, inspire and empower those around her. Everyone has the potential to achieve their dreams and goals, but often can not, because of their fears, perceptions and circumstances. Dr. Mak strives to work with their patients to eliminate barriers that patients can seize opportunities and make life they want a reality.


  1. “Perspectives on labor and income: Reconciliation of life of shift workers.” Statcan.gc.ca. N. P., 2015. Web. May 20, 2016.
  2. Udoh, Uduak et al. “The molecular circadian clock and alcohol-induced liver injury.” Biomolecules 5.4 (2015): 2504-2537. Web.
  3. Okubo, Naoki et al. “Parathyroid hormone resets the circadian clock cartilage organ-cultured murine femur”. Acta Orthopaedica 86.5 (2015): 627-631. Web.
  4. Reinke, Hans and Gad Asher. “Circadian Clock Control of metabolic functions of the liver.” Gastroenterology 150.3 (2016): 574-580. Web.
  5. Nagy, A. D. and A. B. Reddy. “Time dictates: Emerging Clinical Analysis of the impact of circadian rhythms on diagnosis, prognosis and treatment of the disease.” 15.Suppl_6 Medicine Clinic (2015): S50-S53. Web.
  6. Johansson, Anne-Sofie et al. “Disruption of circadian clock gene expression in patients with schizophrenia.” Schizophrenia Research (2016): n. p. Web
  7. Videnovic, Phyllis C. Zee and Aleksandar. “Consequences of circadian disruption in neurological Health”. Clinical Sleep Medicine 10.4 (2015): 469-480. Web.

The Having a regular schedule means you will live a healthier, longer life. appeared for the first time in NaturalPath .

This article was originally published on thenatpath, Read the original article here

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