At home cognitive rehabilitation can help cognitive symptoms in multiple sclerosis

Apr 15, 2016 | | Say something

At home cognitive rehabilitation can help cognitive symptoms in multiple sclerosis ;

demyelination by MS. The CD68 colored tissue shows several Macrophages in the area of ​​the injury. original scale 1: 100. Credit: Marvin 101 / Wikipedia

Cognitive impairment is one of the main symptoms of multiple sclerosis (MS) -and one of its most troubling concerns for many people with disease. Now, a new study Langone NYU Medical Center can provide hope for the symptomatic relief of some of the cognitive problems associated with neurological disease.

In a randomized controlled trial, people with MS who use a training program cognitive remediation based on the computer at home for 12 weeks had results significantly higher than cognitive tests a computer program used placebo. The new research was presented on 17 April at the American Academy of Neurology 68th Annual Meeting in Vancouver.

“This trial shows that cognitive therapy based computer with access from home can be effective in improving cognitive symptoms of people with MS,” says lead study author Leigh Charvet, PhD, associate professor in the Department of MS neurology and director of Research at the University of New York Langone multiple sclerosis Comprehensive Care Center. “The remote delivery of a test and the results of cognitive benefit in the home can also be generalizable to other neurological conditions that compromised cognitive function.”

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Cognitive problems in MS can affect memory, attention and concentration, information processing, verbal fluency and executive function, according to the National Multiple Sclerosis Society. Problems of people with MS may experience include difficulty finding the right words and keep up in conversations, or trouble remembering routines at home or at work. These changes may be related to atrophy and loss of volume in the gray matter of the brain, researchers say.

Previous studies showed that rehabilitation programs or cognitive training to reverse cognitive decline, offer potential benefits for people with MS. However, to ensure maximum benefit, many of these programs require treatment sessions in person in an outpatient setting several times a week for at least an hour. This can be difficult for people with MS who are unable to take time off from work or those associated with the disease that can not easily get to a doctor’s office disabilities.

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To test the efficacy of a treatment intervention cognitive remediation at home, 135 people with MS who were experiencing cognitive problems were randomized to receive either active, computerized training program ( 71 participants) or placebo program with regular computer games (64 participants).

The program of cognitive rehabilitation training used in the study was a version of brain research HQ of Posit Science, in which patients are instructed to play a series of games and tasks. Participants from both groups to train for an hour per day, five days a week for 12 weeks was requested. technical support and weekly training sessions were provided by a technical study.

People with MS who engage in cognitive therapy through improved brain HQ 29 percent on neuropsychological tests, compared to 15 percent improvement for those in the placebo group. While improvement was observed through a series of specific cognitive measures in the active group, there was no registered in the activities of daily life improvements.

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Researchers also argue that the superiority of the program over the placebo group was clear, and the active group in the study would probably still had higher profits than had been supported in the study as the placebo group, which engages the computer program an average of 19 hours more than their counterparts in the study.

“Many patients with MS do not have the time or resources to reach the clinic several times a week for cognitive therapy, and this research shows remotely- supervised cognitive training can be successfully provided people with MS home “According to a study, lead author Lauren B. Krupp, MD, professor of neurology and director of the Center comprehensive Care multiple sclerosis. “Future studies will look at patients with MS may respond more to cognitive therapy, and whether these improvements can be improved or maintained for longer periods of time.”

This article was originally published on medicalxpress, Read the original article

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Posted in: Neuroscience

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